Epithalon

Epithalon is a synthetic version of a peptide originally isolated from the pineal gland, a small endocrine organ involved in circadian rhythms and aging processes. It has attracted attention for its potential role in cellular aging, telomere maintenance, and longevity-related research.

Areas of research interest include: Healthy aging; Cellular longevity; Sleep and circadian rhythm regulation; Immune system modulation.

Epithalon has been shown in laboratory studies to activate telomerase, an enzyme that helps maintain telomeres—the protective caps at the ends of chromosomes. Telomeres shorten as cells divide, and this shortening is associated with aging.

Epithalon has shown low toxicity in experimental studies.

While no standard dosage has been established, a common research dosing protocol for epithalon is 5 mg daily, administered by injection under the skin (subcutaneous). Shown for education only; a licensed clinician should set any actual dose. See the dosing section.

Wipe the vial tops with alcohol, add bacteriostatic water slowly so it runs down the inside of the glass, then roll the vial gently until the powder dissolves; don’t shake it. See the step-by-step guide with diagrams for the pen and syringe methods.

There is no single correct amount. We recommend 2.1 mL: about 0.1 mL is lost during transfer, leaving roughly 2.0 mL of usable solution. You can add more or less (most peptide vials hold up to 3 mL); just enter the amount in the dose calculator. See the step-by-step mixing guide.

No. Epithalon is not FDA-approved in the US (status as of October 2026).